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5-HTP or "hydroxy L-tryptophan" (5-Hydroxytryptophan) is a naturally-occurring amino acid and is the forerunner and also metabolic intermediate in the biosynthesis of the natural chemicals serotonin and melatonin from tryptophan. 5-HTP is converted to the natural chemical serotonin (5-HT), with the help of vitamin B6. This takes place both in anxious tissue as well as in the liver. 5-HTP goes across the blood-brain obstacle (while 5-HT does not). Supplementation with 5-HTP as a result enhances production of Serotonin.

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